100 Books Like How the Brain Lost Its Mind

In this classic book, Kuhn introduces the idea of a "paradigm" and shows that real progress comes through paradigm shifts.

That hit me like a rock when I first read it. I love how in the second edition, Kuhn talks about the difficulties of deep change: "the problem is that the new paradigm is always worse than the old one." 

The new paradigm may be better in some way, but it is also sketchy, unformed, and it creates lots of new uncertainties. So, for somebody to shift to a new paradigm always requires a leap of faith!

This book explains the tight connection between Alzheimer’s disease and education, health, income, and environment, and why the rate of Alzheimer’s disease in the population actually decreased in the decades following the most important societal changes enacted after World War II. Social safety, environmental protections, and income inequality have had far greater impact than any of the pharmacological approaches ever attempted. The authors make the compelling case that brain health is intimately connected to societal health.

Stan Prusiner received the Nobel Prize of Medicine in 1997 for identifying what at the time was considered a novel mechanism of neurodegeneration: the prions. These “infectious proteins” were responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease. Although I have come to doubt that prions are a cause of rapidly progressive dementia and may instead represent a consequence, Prusiner’s memoir is filled with moments of skepticism, self-doubt, adversity, and intellectual rivalries –the ingredients for a gripping drama in neurosciences. 

This collection of essays blew my mind. Researchers in a range of disciplines were asked to elaborate on why a given idea in their field should be put to rest. There is a chapter dedicated to big data, nature versus nurture, cause and effect, race, Linnaean classification, etc. The book’s essays inspired me to shape a section on “Reductionism and related ideas that will die” as part of a solicited article I wrote with Tony Lang in 2018 aiming to predict the future of Parkinson’s disease research in the 2020s (Ben Stecher credited it as his reason to relocate to Cincinnati to work with us in our CCBP study). This book is also a reminder that progress requires new ideas, and most cannot emerge without first abandoning outdated ones (as Kuhn articulated).  

An idea that must die in neurology is the clinico-pathologic model of classifying neurodegenerative diseases: abnormalities on brain… show more.

I truly loved this book because Dr. Daniel Amen is the best in his class. He is a dedicated brain scientist, author, and life changer. I’ve read all of his books because they teach us all how to benefit our brains to change our lives forever.

This book has helped me personally, and so has his research. He's a personal friend and one hell of a game-changer when it comes to recognizing the importance of altering the conversation from mental health to brain health.

He is an important figure of this or any time; the world is lucky he's here to make us all better, one brain at a time. 

This fascinating book is essentially the story of prefrontal lobotomies and the surgery that was developed to carry out the procedure. Although it did help certain violent patients, it had serious side effects not recognized initially and was used inappropriately on too many patients (including President Kennedy’s sister).

The book recounts the history of why the procedure was developed and many of the scientists and surgeons involved. It provides a perfect case study of the caution needed when a new, thought to be miraculous, treatment for any disease is first tried.

We neuroscientists know a lot about how brains are, but not how they come to be. This book fills that huge hole: it explains how genetics and development shape the growing brain, and the consequences this has for our personalities and our mental disorders. Mitchell’s thesis is that the stochastic nature of development is key to understanding much of the variation between brains, and it has changed the way I think about the wiring of brains.

This book picks up brilliantly from where Zero to Birth leaves off. It’s the story of how the brain encodes the reality of the world outside the womb, how our experiences change the brain, and how we acquire knowledge, skills, and sociability.

I found this book to be extremely readable. It’s full of fascinating and illustrative examples of how the human brain continues to change to function effectively in the real world. 

The opening paragraph of this book is pure poetry in motion, putting me in a trance and craving to read the entire book. 

You wouldn’t know this is a book about neuroscience when reading the opening lines in Chapter 1. Connectome is a thought-provoking exploration of the brain's neural connections and their potential to transform our understanding of ourselves and our place in the world. 

Given that artificial intelligence is inspired by neuroscience it’s a great book to understand how the brain works.

V. S. Ramachandran is a gifted experimentalist and writer who does not hesitate to pursue deep and important questions about our minds. Rather than employing expensive imaging or large sample sizes, he is more likely to use a cardboard box, an old stereopticon, or a rubber hand in his experiments. 

His creativity in finding concrete ways to test seemingly vague but interesting claims about our minds has led to several breakthroughs, in our understanding of phantom limbs and our ability to treat phantom pain, and also in our study of synesthesia—cases in which people see numbers as having colors, for example.

As I can attest, he is able to transmit to his students the idea that pursuing scientific questions can be thrilling, fulfilling, and so much fun that you can’t wait to get to work in the morning.