Books like Darwin's Plots

I love Surely You're Joking, Mr. Feynman! because Feynman treats every locked thing as an invitation, and the people guarding it as part of the puzzle.

I laughed through the safe-cracking at Los Alamos, but what stayed with me was how he worked: the combinations were left at the factory setting, and the secrets were guarded mostly by people's belief that they were. Then the last chapter, on cargo cult science, turned the joke on me.

I still use its first rule: you must not fool yourself, and you are the easiest person to fool.

James Watson was a clever, pushy, and critical young American molecular biologist exposed to the scientific culture of Britain in the early 1950s.

The book is full of acerbic comments about “stuffy” Cambridge dons and the rules of etiquette that young Jim struggled with, all the while scheming to maintain the various fellowships that allowed him to remain in the UK and pursue his ambition: to understand the chemical nature of the genetic material, DNA.

The book provides a lively account of his collaboration with an older Brit, the brilliant Francis Crick, who was also trying to unscramble DNA. Much of the technical stuff will be incomprehensible to most, but the method the two followed is clear. The partnership was hugely fruitful and the book is a lively account of how science actually works.

Watson and Crick tried everything while coping with competitors and their criticisms as well as their… show more.

Ritchie was part of a team that attempted to replicate a famous study led by a prominent psychologist, Daryl Bem, claiming that people did better on a word memorization test if they studied the words after taking the test.

Ritchie and his co-authors attempted to replicate this study and found no evidence supporting Bem’s claim. This is but one example of a scientific crisis in that attempts to replicate influential studies published in top peer-reviewed journals fail nearly half the time. Ritchie explains and illustrates the reasons for the current replication crisis in science.

Experimental Medicine is a classic, a clear and simple account of physiological research, well-illustrated with comprehensible examples (no molecular biology needed).

It is well worth reading if only because so many of the principles that French physician Claude Bernard pioneered have been largely forgotten. Most important is his demand for certainty: “Science permits no exceptions,” an injunction now more often forgotten than obeyed. Bernard would have been appalled by, for example, a famous choice experiment in which 60% of a large group of subjects choose a less-profitable option.

The experimenters concluded that individual humans (not just groups) show risk aversion, ignoring the 40% who did not. In a similar situation, Bernard would always seek the conditions that yield a 100% result. He gives an example where he was able to resolve uncertainty concerning the sensitivity of spinal roots.

We’re still waiting for any serious effort to achieve a Bernardian… show more.

Yara is a girl with a passion for science who is determined to make new discoveries. The book has educational back matter explaining the scientific method of making new discoveries and lays out each step in the process clearly that young readers can follow. It will inspire children to start experimenting on their own. Like every good scientist, Yara starts with a question, makes observations, and comes up with a hypothesis... but each time she starts an experiment, her dog, Renzo, ruins it! Yara sets a great example for young readers to pursue scientific studies. In this humorous story, there is clear evidence that scientific method works as well for dogs as for people. 

“Why most published research findings are false” was a 2005 paper that kicked off a crisis in science about failures to replicate, creating gaping cracks in the bedrock of science. Science Fictions explains this replication crisis and prescribes remedies. The book is written in an entertaining style, which led to its inclusion in the shortlist of the Royal Society Science Book Prize for 2021. Psychology is the poster child for the replication crisis. One of the things I like about genetics is that its findings consistently replicate, beginning with the fundamental finding that about half of the differences between people on psychological traits can be explained by inherited DNA differences.

A book about pharmaceutical corruption and manipulative science can rarely make me laugh out loud, but Bad Science does just that.

Not only did the book make me a better advocate for my health by teaching me what red flags to look out for in research and shady science journalism, but it kept me consistently entertained to the point where I was disappointed when the book ended. It should be required reading in all high school science classes. 

This is an excellent series of essays on the small things in life which please the author. Some are more obvious than others, but all are described stylishly and with typical French humour and elegance. I confess that after reading it, I did my own—inevitably inferior—version. But it was an enjoyment just going through the process.

This book has always been one of my all-time favorites because I love the clarity of Lewis’ writing and it deals with the real-world challenges faced by scientists in general and medical doctors in particular. The moral, financial, and romantic dilemmas faced by Martin Arrowsmith constantly keep my teeth on edge as I read this book, never leaving me starved for excitement or something unexpected at every turn. I love how Martin personally transforms throughout the novel and deals in various ways with the emotional challenges of different types of romantic relationships as he faces the obstacles within his career that ultimately shape his internal moral fiber. 

I keep The Demon-Haunted World close because it gave me a toolkit I use far outside science.

Sagan's dragon in the garage, invisible, silent, undetectable, is the best lesson I know in noticing when a claim has been built so that nothing can ever test it.

I first read it for the skepticism and returned to it for the tenderness: he is never contemptuous of the people who believe, only patient with them. It taught me that seeing clearly is a kind of kindness, not a weapon.