Books like An Introduction to the Study of Experimental Medicine

I love Surely You're Joking, Mr. Feynman! because Feynman treats every locked thing as an invitation, and the people guarding it as part of the puzzle.

I laughed through the safe-cracking at Los Alamos, but what stayed with me was how he worked: the combinations were left at the factory setting, and the secrets were guarded mostly by people's belief that they were. Then the last chapter, on cargo cult science, turned the joke on me.

I still use its first rule: you must not fool yourself, and you are the easiest person to fool.

James Watson was a clever, pushy, and critical young American molecular biologist exposed to the scientific culture of Britain in the early 1950s.

The book is full of acerbic comments about “stuffy” Cambridge dons and the rules of etiquette that young Jim struggled with, all the while scheming to maintain the various fellowships that allowed him to remain in the UK and pursue his ambition: to understand the chemical nature of the genetic material, DNA.

The book provides a lively account of his collaboration with an older Brit, the brilliant Francis Crick, who was also trying to unscramble DNA. Much of the technical stuff will be incomprehensible to most, but the method the two followed is clear. The partnership was hugely fruitful and the book is a lively account of how science actually works.

Watson and Crick tried everything while coping with competitors and their criticisms as well as their… show more.

Ritchie was part of a team that attempted to replicate a famous study led by a prominent psychologist, Daryl Bem, claiming that people did better on a word memorization test if they studied the words after taking the test.

Ritchie and his co-authors attempted to replicate this study and found no evidence supporting Bem’s claim. This is but one example of a scientific crisis in that attempts to replicate influential studies published in top peer-reviewed journals fail nearly half the time. Ritchie explains and illustrates the reasons for the current replication crisis in science.

Any list of books about science must have something about Darwin. The book to read is The Origin. But that’s obvious. I don’t need to go into it. So here is a Darwin book that is less obvious.

Most scientists will never have heard of it; it’s literary history, not science. I learned of it by accident, in a talk given by an economic historian. This is a fascinating book by a literary historian from which I learned much about Darwin. Gillian Beer recognizes that Darwin was a great writer. She traces similarities between his rhetorical style and the strategies of some other iconic Victorian writers, such as George Eliot (Middlemarch) and Samuel Butler (The way of all flesh).

She also discusses scientific writers of the era such as George Lewis and Herbert Spencer. There are many revealing long quotations. I learned much from the… show more.

This classic 1966 movie and the novelization by SF icon Isaac Asimov really hooked me on science fiction. So much so that I later felt compelled to write an hommage to it. Travelling through the human bloodstream? Being attacked by antibodies and white blood cells? Irresistible! One of the things SF does best is to show us familiar things from an entirely new perspective, and Fantastic Voyage did that in spades with a premise that was outlandish but completely serious and groundbreaking. Although Asimov wrote the novel version from the screenplay, it was released before the movie and it’s difficult to separate the two. I really recommend enjoying both.

Asimov later wrote a novel of his own (not a sequel) called Fantastic Voyage II: Destination Brain published in 1987, but it isn’t all that memorable.

Known only to true devotees of medical ethics and the history of human research, Jay Katz’s hefty volume (1,150 pages) is a comprehensive encyclopedia of humans used as research material. Information-packed chapters cover everything from Chester Southam’s use of senile hospital patients in cancer cell injection studies during the 1960s, and the legal fallout from such indiscretions, to the ethical obligations of researchers, and the evolution of informed consent as a pillar of ethical human research. Impressive in both detail and scope, this imposing piece of scholarship is a valuable resource for anyone looking to learn the many moral and legal issues inherent in experimenting on humans. 

In this gripping courtroom drama, an explosion in Miracle Creek, Virginia, destroys the business of South Korean immigrants Pak and Young Yoo and puts their daughter Mary into a monthslong coma. As arguments mount against the woman accused of starting the fire, Young struggles with a question many immigrants must face. Maybe she shouldn’t have brought her child to the US, where Mary struggles as a teenager and where she was almost killed. The tension between the two generations resonated with me as a parent and immigrant. As Young hopes to discover who caused the explosion that killed two other people, she must also help Mary imagine a future in their adoptive country.

This book was such fun to read! It's really unusual in that it's told entirely by letters, emails, and text messages. It has no chapters and invites lots of flicking pages back and forth to go back and check things, so it's super interactive (I was glad I got the paperback!). I really liked that most of the characters are unlikeable, and none of them seem to like each other very much, either. I LOVE unlikeable characters.

On top of that, much of the information they give in the letters is unreliable at best or completely untrue at worst. This book is a murder mystery, but it takes ages to find out who's dead, and by the time I found out, I'd wanted most of the characters to have been killed off–they really are a nasty lot! This book was totally original and very clever, and I adored it from… show more.

“Why most published research findings are false” was a 2005 paper that kicked off a crisis in science about failures to replicate, creating gaping cracks in the bedrock of science. Science Fictions explains this replication crisis and prescribes remedies. The book is written in an entertaining style, which led to its inclusion in the shortlist of the Royal Society Science Book Prize for 2021. Psychology is the poster child for the replication crisis. One of the things I like about genetics is that its findings consistently replicate, beginning with the fundamental finding that about half of the differences between people on psychological traits can be explained by inherited DNA differences.

A book about pharmaceutical corruption and manipulative science can rarely make me laugh out loud, but Bad Science does just that.

Not only did the book make me a better advocate for my health by teaching me what red flags to look out for in research and shady science journalism, but it kept me consistently entertained to the point where I was disappointed when the book ended. It should be required reading in all high school science classes.