100 Books Like As Gods

I love this book because it turns the most impactful science discovery of the 21st century–CRISPR gene editing–into a page-turner. Isaacson combines a biography of Jennifer Doudna, who shared the 2020 Nobel Prize in Chemistry with Emmanuelle Charpentier, with lucid accounts of the science and sequence of research breakthroughs that underlie CRISPR editing, as well as the intrigues and jockeying among powerful scientists and personalities vying for prizes and patents on the technology.

I came through this book to appreciate the enormous potential of CRISPR gene editing for good (curing hereditary diseases) and not-so-good (designer babies or, in the words of Vladimir Putin, “a soldier, an individual who can fight without fear or compassion, mercy or pain”). CRISPR promises to make human selection as important as natural selection in the evolution of many species, including humans.

Once upon a time, we were unaware of DNA. We could tell that taller parents have taller kids, we could select tomato plants for sweeter fruit, and we could even construct plausible relationships between long-extinct animals and their descendants. Still, the nature of the stuff from which these links are made and how it works or fails to work remained a mystery.

Solving this mystery is one of humanity’s most remarkable achievements, and Mukherjee tells the tale with style and humor, weaving in recollections of his family’s encounters with mental illness. Despite my familiarity with the end result, the modern picture of genes, I found much of the history surprising and surprisingly colorful, full of dead ends and creative leaps. The last third of the book, on complex traits like intelligence and illnesses like schizophrenia, isn’t quite as good as the rest, but that takes us to our second… show more.

A Crack in Creation was the first mainstream book that conveyed the extraordinary potential and ethical peril of the new genome editing technology, CRISPR. And who better to write it than the scientist who co-developed the “genetic scissors”, Professor Jennifer Doudna (who won the Nobel Prize three years later).

The book is also notable for the candid manner in which Doudna discusses her own nightmares about the potential misuse of CRISPR – fears that erupted one year later in the ‘CRISPR babies’ scandal.

The CRISPR story took a shocking turn in 2018 when a Chinese scientist attempted the unthinkable – overseeing the birth of twin girls with edited DNA.

I devoted multiple chapters to this saga in my book (resulting in the book’s ban in China); meanwhile, Stanford law professor Hank Greely produced an excellent account of the entire story in CRISPR People. Greely eloquently guides the reader beyond the headlines, offering valuable context and shrewd legal analysis, before asking whether this scandal could happen again.

Somewhat paradoxically, this treatise against genetic enhancement starts with the case of a deaf couple who want to have a deaf child.

This is a case I often discuss in exploring the difference between disease, disability, and diversity. Following on from this case description, Sandel asks, “Is it wrong to make a child deaf by design?” And what if the desired trait was not deafness but height, athletic prowess, health, or intelligence, and the aim was to gain a competitive advantage?

Would your answer be the same? In the pages that follow, Sandel builds a case against “reengineering our nature” grounded in an ethic of giftedness (i.e., a reverence for life as a gift).

He eschews the drive to mastery and insists that “[t]o appreciate children as gifts is to accept them as they come, not as objects of our design, or products of our will, or instruments of our… show more.

I think Zachary Shore is one of our most underappreciated, insightful interpreters of American and global history.

Shore impressed me with his unique method of examining micro-events that give us a much wider view of American culture. He shows how America, at its best, can be a strong and moral guiding force for good in the world, but he doesn't shy from divulging the darker sides of the American psyche, such as the blunders that lead American leaders to make terrible and consequential military decisions.

Shore is not only a great historian but also a gifted writer. This book showed me how the collective memory of our nation has been portrayed too often in flawed stereotypes, either a villainous, youthful colossus or a city on a hill, a shining example for the rest of humanity. Shore convinced me that at its root, America can be a force for good as… show more.

Jacob Needleman’s Money and the Meaning of Life is the most influential and inspiring book by far for the development of life planning movement in financial advice.

A masterful storyteller with his own set of characters, Needleman guides us into the mystery of how money works and what money is really about. Going back and forth between money’s practicalities and the deeper longings we all have for freedom, he challenges us to explore what freedom really means in relation to money.

A page-turner of speculative philosophy, I can still remember how gripping the final 20 pages were. In his exploration of money and meaning, Needleman tells the story of life planning, which is the story of each of our aspirations for freedom, and then the path to accomplish them. 

Scully's tour de force investigates the state of humanity's relationship with animals through a Scriptural lens, exploring the multifaceted concept of "dominion" from the Biblical creation story as he takes on industrial farmers, trophy hunters, and others who gain fame and fortune on the backs of suffering nonhuman creatures.

I continue to be moved by the author's courage in using his voice as a well-known Republican speechwriter to dismantle the notion that compassion for animals is a "liberal" cause. His immersive research into the full range of manifestations of animal cruelty makes this one of the most shocking and compelling texts I have read on the subject of our treatment of other beings. 

This remarkable story illustrates that if something in healthcare sounds too good to be true, it probably is. I had to stop listening to it before going to sleep because the compelling narrative was keeping me up at night.

The author seamlessly combined this compelling narrative with exceptional research behind the Food and Drug Administration, the heroine who prevented thalidomide approval in the United States, and the catastrophic effects of a pharmaceutical company using loopholes.

This book asks policymakers to look beyond incentives when designing policies.

Whether we are trying do something at a personal level, such as have our children do chores, or achieve something much bigger, such as combat obesity, designing appropriate incentives (carrots or sticks) is generally believed to help us achieve our goals.

Bowles warns us that this view assumes that incentives and morality are independent and that such view is faulty. Numerous experimental evidence attests to his argument. In its stead, he suggests shaping norms as a much more viable option.

When I presented these concepts in my economics elective this semester, one student commented that this was a “paradigm shift” in their understanding of economics; hence, the reason why I recommend this book.