Book cover of The Poisoner's Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York

Book description

Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer

“The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times

“Reads like science fiction, complete with suspense, mystery…

When you buy books, we may earn a commission that helps keep our lights on (or join the rebellion as a member).

Why read it?

2 authors picked The Poisoner's Handbook as one of their favorite books. Why do they recommend it?

I love that this reads like a gritty detective novel, but it also reveals how two New York scientists virtually invented forensic toxicology during prohibition and the Jazz Age. Before their pioneering work, a poisoner could easily get away with murder; medical examiners had no way to detect deadly compounds like arsenic, mercury, cyanide, or thallium, even if they suspected foul play.

I found Blum’s depiction of true-life criminal cases and the work of the medical investigators hard to put down.

A fun romp through many famous cases where “he done her in” (or vice versa) by such varied poisons as arsenic, strychnine, potassium cyanide, cyanide of mercury (even deadlier than potassium!), with an analysis of the policing and chemists’ methods used to nab the perpetrators. Not as common today as in the late nineteenth and early twentieth centuries, death by poison was once the preferred, most devious, means for people to eliminate their enemies, ex-lovers, husbands, and wives. Taste that drink before you down it!

If you love The Poisoner's Handbook...

Book cover of The Rosewood Penny

The Rosewood Penny by J.S. Fields,

2023 Queer Indie Award Nominee!

The dragons of Yuro have been hunted to extinction.

On a small, isolated island, in a reclusive forest, lives bandit leader Marani and her brother Jacks. With their outlaw band they rob from the rich to feed themselves, raiding carriages and dodging the occasional vindictive…

Want books like The Poisoner's Handbook?

Our community of 12,000+ authors has personally recommended 100 books like The Poisoner's Handbook.

Browse books like The Poisoner's Handbook

Book cover of The Making of the Atomic Bomb
Book cover of A Pickpocket's Tale: The Underworld of Nineteenth-Century New York
Book cover of The Gilded Age in New York, 1870-1910

Share your top 3 reads of 2025!

And get a beautiful page showing off your 3 favorite reads.

1,343

readers submitted
so far, will you?

📚 If you like The Poisoner's Handbook, you might also like...

Book cover of Portrait of an Artist as a Young Woman

Portrait of an Artist as a Young Woman by Alexis Krasilovsky,

Kate from Jules et Jim meets I Love Dick.

A young woman filmmaker’s journey of self-discovery, set against a backdrop of the sexual liberation movement of the 1970s and 1980s. In Portrait of an Artist as a Young Woman, we follow Ana Fried as she faces the ultimate…

Book cover of Malcolm Before X

Malcolm Before X by Patrick Parr,

Malcolm Before X is about finding a way to continue moving forward after everything has been taken from you. While in prison, Malcolm Little discovered the power of reading and found a way to transform his character and become a better man. This half-biography focuses on that transformation, especially his…

5 book lists we think you will like!