Will I love The Ghost in the Addict?

Shep Siegel conducted ingenious experiments in the 1970s demonstrating that drug tolerance in rats is largely if not entirely due to Pavlovian conditioning: The experienced drug user responds to indicators that a dose is imminent with physiological counter-responses that lessen the impact of the drug. Almost from the get-go, Siegel saw the potential relevance of his research to aspects of addiction, withdrawal, and relapse in human beings, but it has taken addiction researchers decades to assimilate the implications, which are profound.
Now retired, Siegel has written a highly readable retrospective account of this story which I found utterly convincing, and… show more.